Knowledge put into action started bearing marvelous fruits. Dr. Madhu Loomba established the Madhuraj Advanced Infertility & IVF-ICSI centre in the year 2000 and just after one year, the first test tube baby of Kanpur city was born to the couple in the centre under the medical guidance and supervision of Dr. Madhu Loomba. The news was widely covered and prominently published in all the national newspapers. In later years, the first IVF twins and the first IVF triplets were also born in the centre.